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PHARMNOVO IS A BIOPHARMA COMPANY performing research and development in collaboration with internationally leading academic and pharmaceutical scientists in their fields related to pain and pain therapy.
THE PRE-CLINICAL PHASE of the PN6047 development project is fundamentally complete and planning is now in train for regulatory toxicology testing and first in man clinical trials. The regulatory toxicology programme is being designed in collaboration with selected experts who will advise and manage the conduct and analysis of the animal testing.
Clinical input into the remaining phases of the project is clearly necessary and PharmNovo has put together a first class clinical team. The team includes; Andrew Rice, Professor of Pain Research, Imperial College, London; (link), Dr Roger Knaggs, Associate Professor in Pharmacy Practice, University of Nottingham (link), Chair of the UK Clinical Pharmacy Association pain management group) and Dr Peder Andersson, Chief Executive Officer, Biosergen.
Together with Board member Dr Anthony Ford, the team has huge experience of overseeing clinical testing of new drugs, interaction with regulatory bodies and progression to the market.
As the company prepares for the next phase of clinical development, the new Board composition strengthens our strategic capabilities ahead of Phase II development of our lead candidate, PN6047.
Read moreWe are delighted to share that Professor Amynah Pradhan has been awarded a prestigious Endowed Chair at Washington University, where she now serves as the Russell D. and Mary B. Shelden Professor of Anesthesiology.
Read morePharmNovo AB is pleased to announce that the clinical trial application (CTA) for a Phase IIa proof of concept (PoC) study investigating the safety and efficacy of lead candidate PN6047 in patients with neuropathic pain has been approved in Spain. The full title of the study is: “Randomized Double-Blind Placebo-Controlled Cross-Over Trial of the Safety, Tolerability, and Efficacy of PN6047 HCl in Peripheral Neuropathic Pain Characterized by Mechanical Allodynia.”
Read moreBreaking new ground in pain management In the latest episode of BioBizBuzz, PharmNovo CEO Per von Mentzer sits down with host Mike Ward to discuss how we’re tackling one of modern medicine’s most urgent challenges: finding effective, non-addictive treatments for chronic and neuropathic pain. The conversation highlights the development of our lead candidate PN6047, a selective delta-opioid receptor agonist designed to deliver strong pain relief without the addiction risks or sedation associated with traditional opioids. Per shares insights into the scientific rationale, clinical potential, and why neuropathic pain—often caused by nerve damage from conditions like diabetes or chemotherapy—demands new thinking. For anyone interested in neuroscience, biotech innovation, or the future of pain management, this episode offers a glimpse into what could become a paradigm shift in treatment. Listen to the full episode here:
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