Strengthening the team
PharmNovo has strengthened the team with a new experienced Project Manager and a Clinical trial manager to continue the development of the company's drug candidate PN6047 for the treatment of neuropathic pain, so-called nerve pain.
Inge Tarnow joins the team as the new Senior project manager and will lead and coordinate the work with PN6047. Inge Tarnow holds a Ph.D. in pathophysiology and is a Doctor of Veterinary Medicine. She has worked as a project manager at Savara, a biopharmaceutical company focusing on rare respiratory diseases, for six years.
PharmNovo also welcomes Thomas Eskildsen, Senior Clinical Trial Manager. He will oversee the phase I study while being an asset to the team in the planning and managing future phase IIa studies.
Strengthening the team
PharmNovo has strengthened the team with a new experienced Project Manager and a Clinical trial manager to continue the development of the company's drug candidate PN6047 for the treatment of neuropathic pain, so-called nerve pain.
Inge Tarnow joins the team as the new Senior project manager and will lead and coordinate the work with PN6047. Inge Tarnow holds a Ph.D. in pathophysiology and is a Doctor of Veterinary Medicine. She has worked as a project manager at Savara, a biopharmaceutical company focusing on rare respiratory diseases, for six years.
PharmNovo also welcomes Thomas Eskildsen, Senior Clinical Trial Manager. He will oversee the phase I study while being an asset to the team in the planning and managing future phase IIa studies.
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Breaking new ground in pain management
Breaking new ground in pain management In the latest episode of BioBizBuzz, PharmNovo CEO Per von Mentzer sits down with host Mike Ward to discuss how we’re tackling one of modern medicine’s most urgent challenges: finding effective, non-addictive treatments for chronic and neuropathic pain. The conversation highlights the development of our lead candidate PN6047, a selective delta-opioid receptor agonist designed to deliver strong pain relief without the addiction risks or sedation associated with traditional opioids. Per shares insights into the scientific rationale, clinical potential, and why neuropathic pain—often caused by nerve damage from conditions like diabetes or chemotherapy—demands new thinking. For anyone interested in neuroscience, biotech innovation, or the future of pain management, this episode offers a glimpse into what could become a paradigm shift in treatment. Listen to the full episode here:
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CTA submission for PN6047
PharmNovo AB is pleased to announce that the clinical trial application (CTA) for a Phase IIa proof of concept (PoC) study investigating the safety and efficacy of lead candidate PN6047 in patients with neuropathic pain has been submitted in Spain. The full title of the application is: “Randomized Double-Blind Placebo-Controlled Cross-Over Trial of the Safety, Tolerability, and Efficacy of PN6047 HCl in Peripheral Neuropathic Pain Characterized by Mechanical Allodynia.” Based on a strategic company decision, PharmNovo has submitted the CTA, in the first instance, to the Spanish Health Authorities only. Submission to the Czech Republic and Poland, the two other countries in which the trial will be conducted, is planned to take place following approval in Spain, which is expected by October 2025. Subject to additional investment, patient enrolment is expected to start by Quarter 1 2026.
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PharmNovo at the LSX World Congress in London
Take the opportunity to listen to Per von Mentzer, CEO, presenting PN6047 at the LSX World Congress in April 2025 in London. PharmNovo is redefining pain management with PN6047, a first-in-class Delta Opioid Receptor Agonist (DORA), safer, non-addictive solution for neuropathic pain. Unlike traditional opioids, PN6047 eliminates concerns of side effects, abuse potential, and tolerance. With a proven safety profile from Phase I trials and a market projected to exceed EUR 13 billion by 2033, PN6047 is set to be a game-changer.
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Positive FDA feedback for PN6047
PharmNovo has received positive and constructive feedback from the FDA for its lead drug candidate, PN6047, a selective delta opioid receptor agonist aimed at treating peripheral neuropathy with allodynia. Following a successful pre-IND meeting in January 2025, the FDA provided valuable guidance on the Phase IIa study design and had no critical comments on the CMC or non-clinical data. This paves the way for IND submission by the end of 2025 and a Phase IIa clinical trial application in Europe (Spain, Poland, Czech Republic) by Q3 2025.
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